Why is clozapine a last resort

Why is clozapine a last resort

The 97 patients with complete aims data showed a mean improvement of 16.6 percent in total score.Like most antipsychotics, it works by blocking dopamine receptors in the brain.Hill r, krum h (2007).A noted side effect of clozapine is agranulocytosis, which requires a weekly complete blood count with differentials.40 the normal clinical approach is to identify and manage aes if possible and to discontinue clozapine only as a last resort.I was on topiramate initially at 450 mg alongside clozapine.

I am sorry if i am wrong about that information but i was told that it was a last resort because of the weight gain and other side effects, some lethal.Not a 'last resort.' american psychiatric association treatment guidelines for schizophrenia state:It was working and six weeks later i was discharged from hospital.

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